KAJIAN MENGENAI HABBATUS SAUDA DAN SINUITIS (RESDUNG)

Natural therapeutic approach of Nigella sativa (Black seed) fixed oil in management of Sinusitis

1. The results of investigations on N. sativa seed fixed oil showed its therapeutic potential in treatment of sinusitis by its anti-inflammatory, antioxidant, antihistaminic, immune-modulator, antimicrobial and analgesic effects

2. The use of N. sativa seed fixed oil can inhibit the inflammation of sinuses and respiratory airways, microbial infections and finally help the patients suffering from clinical symptoms of sinusitis such as coryza, nasal congestion, headache, neck pain, earache and toothache

3. The seeds contain amino acids, proteins, carbohydrates, 0.4-1.49% essential oil, 30-44.21% fixed oil, sterols (cholesterol, campestrol, stagmasterol, α-spinasterol, β-sitosterol) , alkaloids (nigellidine, nigellimine, nigellicine), saponins and crude fiber, minerals (calcium, iron, sodium, potassium) . Thymoquinone (26.8-54.8%), p-cymene (14.7-38.0%), longifolene (1.2-10.2%), α-thujene (1.3-10.1%), carvacrol (0.5-4.2%), α-cubebene (0.4-3%), α-pinene (0.2-2.4%), limonene (0.7-2.3%), β-pinene (0.4-3.0%), sabinene (0.2-1.6%) were the main components of N. sativa seed essential oil . Linoleic acid make up 50% of fixed oil, followed by oleic acid (25%), palmitic acid (18%). Thymoquinone (2-isopropyl-5-methyl-1,4-benzoquinone) is present at concentration of 3.5-8.7 mg/g in fixed oil

4. Sinusitis is associated with inflammation of sinus cavities as the result of an irritant or triggering the body's histamine responses.

Therefore, the anti-inflammatory, anti-histaminic and antioxidant effects of N. sativa seed fixed oil may explain one of mechanisms related to its efficacy in reducing the inflammation of sinuses and respiratory airways.


5.  The antioxidant, anti-histaminic and anti-inflammatory effects of N. sativa seed fixed oil and main components decrease the inflammation of sinuses and respiratory airways, and inhibit the nasal congestion, edema, coryza as the clinical signs of sinusitis.


SUMBER
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884000/

KAJIAN MENGENAI KHASIAT BAWANG PUTIH

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